This is an expanded and updated report that includes:
  - 55 New Pages of Material
  - Updated Charts, Timelines, Metrics and Financials
  - 5-Year Projection Data
  - Expanded Competitive Environment Analysis
  - Detailed Characterization of the Market, Emphasizing Statistical Trending
  - Exploration of Recent Product Evolution and Projected Directions for Development
  - Overview of Therapeutic Progress and Insight into Future Applications
  - Detailed Evaluation of Profit Opportunities
  - New Section on End-User Interests, Needs, Technical Preferences (Scientist Panel)

TABLE OF CONTENTS

I. Abstract

II. Overview

    A. Definition
    B. Alternative Nomenclature
    C. Identification

          1. Characteristics
          2. Functional Attributes

    D. Benefits Relative to Other Stem Cell Types

III. Sources

    A. Fetal
    B. Adult

IV. Cell Types Derived from MSCs

V. Applications

    A. Basic Research Applications

          1. Directed Differentiation of Autologous MSCs to Intra-Mesenchymal Lineages

          2. Directed Differentiation of Autologous MSCs to Extra-Mesenchymal Lineages

    B. Supporting Hematopoietic Cells

    C. Gene Transfer Applications

    D. Cell-Based Therapy Applications

          1. Overview

          2. Major Applications

              a. Osteogenic-Focused Research Labs
              b. Myogenic and Myocardial-Focused Research Labs
              c. Adipogenic-Focused Research Labs

      3. Therapeutic Potential Beyond Mesenchymal Lineages

              a. Neural-Focused Research Labs
              b. Diabetic Treatment Applications

    E. Use of MSCs in 3-D Scaffolds for Tissue Engineering Applications

    F. Drug Delivery Applications: Engineered MSCs as carriers of anti-cancer drugs

    G. Drug Screening

    H. MSC-mediated Inhibition of Immune Effector Cells

VI. Application Priorities

    A. Overall

    B. By Segment

          1. Academic
          2. Biotech
          3. Pharma

VII. Companies Offering Human MSC Research Products

    A. Abcam
    B. BD Biosciences
    C. Celprogen
    D. Cyagen Biosciences (China only)
    E. Invitrogen
    F. LGC Standards/ATCC
    G. Lonza
    H. Millipore
    I. Miltenyi Biotec
    J. PAA - The Cell Culture Company
    K. PromoCell
    L. SA Biosciences
    M. ScienCell Research Laboratories
    N. STEMCELL Technologies
    O. Thermo Scientific
    P. R&D Systems

VIII. Companies Offering Rodent MSC Research Products

    A. Cell Applications
    B. Celprogen
    C. Cyagen Biosciences (China only)
    D. Genlantis
    E. Millipore
    F. Miltenyi Biotec
    G. ScienCell Research Laboratories
    H. Trevigen, Inc.

IX. Analysis of MSC Research Activity

    A. By Source

    B. By Clinical Application

    C. By Species

    D. By Country of Research

X. Market Trend Analysis

    A. Trailing 5 Years Data

          1. Scientific Publication Rate Analysis
          2. Grant Trend Rate Analysis
          3. Patent Analysis

    B. 5-Year Projection Data

          1. Scientific Publication Rate Analysis
          2. Grant Trend Rate Analysis
          3. Patent Analysis

XI. Mesenchymal Stem Cells as Tools for Drug Discovery

    A. Companies Developing Toxicology Screening Platforms for Stem Cells

    B. Potential Drug Screening Advantages of Rat MSCs

          1. Acquisition, Handling, and Differentiation Advantages

          2. Genetic Manipulation of MSCs

          3. Potential for Genetically Engineered MSC Reporter Lines

XII. Serum Free Supplements for Use in MSC Research

    A. Invitrogen, Inc.
    B. Celprogen
    C. Millipore, Inc.
    D. STEMCELL Technologies
    E. U.S. Patent 7109032: Serum-free medium for MSCs (Genoa, IT)

XIII. Potential Labs/Customers

    A. By Research Area

          1. General MSC Research Labs

          2. Osteogenic-Focused Research Labs

          3. Myogenic and Myocardial-Focused Research Labs

          4. Adipogenic-Focused Research Labs

          5. Neural-Focused Research Labs

          6. Immunology-Focused Research Labs

      B. By Industry Segment

          1. Commerical Labs

          2. NIH Labs

          3. Academic

XIV. End-User Preferences (Scientist Panel)

    A. Source Preference

    B. Species Preference

    C. Auxiliary Product Preferences

    D. Most-Commonly Used MSC Antibodies

XV. Research Product Opportunities & Suggestions

    A. RMSCs (Rat MSCs) Derived from Alternative Sources than Bone Marrow

    B. Novel RMSC Differentiation Kits

    C. Mesenchymal Stem Cell Expansion Media

    D. Antibodies to Mesenchymal Stem Cell Markers

    E. Mesenchymal Growth Factors

    F. Monoclonal Antibodies and Kits for Phenotyping RMSCs

    G. Chips for MicroArray Analysis of Gene Expression in RMSCs

    H. Optimized Bioreactors

    I. Clinical Grade MSCs

XVI. Conclusions

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