Table of Contents

I. Applications

A. Basic Research Applications

1. Directed Differentiation of Autologous MSCs towards Intra-Mesenchymal Lineages

2. Directed Differentiation of Autologous MSCs towards Extra-Mesenchymal Lineages

B. Supporting Hematopoietic Cells

C. Cell-Based Therapy Applications

1. Gene Transfer Applications
2. Allogenic Transplantation

3. Applications of MSCs for Osteochondral Repair

4. Applications of MSCs for Myocardiac Repair

5. Therapeutic Potential beyond Mesenchymal Lineages

D. Use of MSCs in 3-D Scaffolds for Tissue Engineering Applications

II. Application Priorities

A. Overall

B. By Segment

1. Academic
2. Biotech
3. Pharma

III. Potential Labs/Customers

A. General MSC Research Labs
B. Osteogenic-Focused Research Labs
C. Myogenic and Myocardial-Focused Research Labs
D. Adipogenic-Focused Research Labs
E. Neuronal-Focused Research Labs
F. Immunology-Focused Research Labs
G. Commerical Labs
H. NIH Labs

IV. Companies Offering Human MSC Research Products, including Products Offered

A. Stem Cell Technologies
B. Thermo Scientific
C. Invitrogen
D. Celprogen
E. ScienCell Research Laboratories
F. Abcam
G. BD Biosciences
F. Millipore

V. Companies Offering Rodent MSC Research Products, including Products Offered

A. Cell Applications
B. Millipore
C. Celprogen
D. Cyagen Biosciences
E. ScienCell Research Laboratories

VI. Projected 5-Year Market Growth

A. Scientific Publication Trend Analysis
B. Grant Rate Trend Analysis
C. Patent Trend Analysis

VII. Mesenchymal Stem Cells as Tools for Drug Discovery

A. Companies Developing Toxicology Screening Platforms for Stem Cells

B. Advantages of Using Human MSCs for Drug Screening

C. Potential Drug Screening Advantages of Rodent MSCs

1. Acquisition, Handling, and Differentiation Advantages

2. Genetic Manipulation of MSCs

3. Potential for Genetically Engineered MSC Reporter Lines

VIII. Advantages of Serum Free Supplements for Use in MSC Research

IX. Research Product Opportunities and Suggestions

A. MSCs Derived from Alternative Sources than Bone Marrow

B. Novel RMSC (Rat MSC) Differentiation Kits

C. Mesenchymal Stem Cell Expansion Media

D. Mesenchymal Stem Cell Markers

E. Mesenchymal Growth Factors

F. Monoclonal Antibodies and Kits for Phenotyping RMSCs

G. Chips for MicroArray Analysis of Gene Expression in RMSCs

X. Conclusions

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