I. BackgroundA. Neuronal Stem & Progenitor Cells
B. Language Surrounding Neuronal Stem & Progenitor Cells
C. Regulation of Neuronal Stem & Progenitor Cells
D. Brief Product Background
II. Applications
A. Basic Research1. Developmental Biology
2. Adult Biology
B. Drug Discovery Applications
C. Drug Delivery Applications
D. Neural Toxicology Assessment
E. Neural Transplantation
F. Brain Tumor Research
III. Application Priorities
A. Overall1. Cell-Based Therapies: Greatest shared priority across research community
2. Standardized Neural Toxicology Assays: Deserve proportionally more attention
B. Breakdown of Neuronal Stem/Progenitor Cell Therapy, by Disorder
- Parkinson's
- Brain Tumor / Glioma
- Stroke
- Spinal Cord Injury
- Alzheimer's
- Other
- Huntington's
- Multiple Sclerosis (MS)
- Epilepsy
- Amyotrophic Lateral Sclerosis (ALS)
- Schizophrenia
- Cerebral Palsy
C. By Segment
1. Academic
2. Biotech
3. Pharma
IV. Patents
A. Key U.S. Neuronal Stem and Progenitor Cell Patents
B. Additional U.S. Patents
C. Additional European Patents
V. Projected 5-Year Market Growth
A. Scientific Publication Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
B. Grant Rate Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
C. Patent Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
VI. Competitors: Suppliers of Neuronal Stem & Progenitor Cell Products, including Products Offered
A. Millipore, Inc.
B. Stem Cell Technologies
C. AlphaGenix, Inc.
D. R&D Systems
E. Cell Applications
F. SA Biosciences
G. ScienCell
H. Neuromics
I. Amaxa
J. Invitrogen
K. Sigma Aldrich
L. Orion (no longer in existence)
VII. Specialty Pharmaceutical Companies: Neuronal Stem & Progenitor Cell Therapies
A. Neuralstem, Inc
B. NeuroNova AB
C. NeuroGeneration
VIII. Breakdown of Stem Cell Research Activity by Cell Type
- Embryonic SCs
- Hematopoietic SCs
- Mesenchymal SCs
- Neural Stem & Progenitor Cells
- Umbilical Cord SCs
- Cancer SCs
- Other SCs
- Fetal SCs
IX. Potential Labs/Customers
A. Academic Labs
B. Private Labs
C. Commercial Labs
D. Government Labs
X. Product Ideas & Suggestions
A. Product Categories 1. Cells & Tissuea. Fetal-Derived Neural Stem Cells
b. Adult-Derived Neural Stem Cells
c. Fetal-Derived Immortalized Neural Stem Cells
d. Cryopreserved Embryonic Neurospheres
e. Embryonic Stem Cell Derived Neural Progenitors
f. Embryonic Primary Neuronal Tissue
g. NSC Differentiated Progeny Cells
2. Kits a. Kits for Analysis of NSC Differentiated Progeny
b. Stem Cell Functional Kits
c. Neuronal Stem Cell Phenotyping Kits
d. Neural Stem Cell Expansion Kits
e. Neural Stem Cell Differentiation Kits
f. Neural Stem Cell Blotting Kits
3. Media: Maintenance, Differentiation, Expansion, & Freezing Medium
4. Growth Factors
5. Markets: Markers for Neural Stem Cells & Differentiated Progeny
6. PCR Arrays
7. Nucleofection Tools
8. Neural Toxicity Assessment
B. Product Suggestions1. Neural Toxicity Assessment Products (an untapped niche)
2. Species-Specific Opportunities
3. Areas of Underdeveloped Competition
4. NSC Derived from Novel Sources
5. Neural Rosette Cells (R-NSCs)
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