Poly(ADP-ribose) polymerase (PARP) Research Products

I. ABSTRACT

II. BACKGROUND

A. Introduction
B. PARP Superfamily

1. Characterized Isoforms
2. Comparison of domain structures of PARP isoforms

C. Active / Inactive States of PARP-1
D. Severity of Damage Regulates Repair Processes
E. Regulation of DNA Repair by NAD
F. PARP-1 Inhibition
G. PARP-1 Degradation by Proteases

III. APPLICATIONS

A. Basic Research

1. Current Applications
2. Future Applications

B. Diagnostic Applications

1. Current Applications
2. Future Applications

C. Future Applications

1. Current Applications
2. Future Applications

IV. PARP MARKET COMPETITION

A.Comprehensive List of PARP Research Product Companies
B. Dominant Competitors

V. MARKET SIZZE DETERMINATION

A. Experimental Approach
B. Annual Worldwide Market Size, Broken Down by Individual Company

VI. MARKET ASSESSMENT

A. Federal Funding for PARP Research
B. Pharmaceutical Development of PARP-1 Inhibitors

1. Inotek Pharmaceuticals
2. Guilford Pharmaceuticals
3. Niadyne Pharmaceuticals
4. Agouron Pharmaceuticals
5. Octamer, Incorporated

C. Private Funding
D. User Consumption of PARP Research Products

1. Geographic Distribution of PARP Research Labs
2. Patents
3. Publications
4. Growth Rate Determination
5. 5 Year Projections
6. Factors Contributing to Market Growth

VII. COMPETITIVE LANDSCAPE

A. Market Opportunities
B. Market Risks

VIII. RESEARCH PRODUCTS OVERVIEW

A. Product Line Divisions
B. Dominant Product Areas
C. Expansion into Related Product Areas
D. Novel Product Opportunities and Suggestions
E. Communication Strategies for Accessing the Marketplace
F. Potential Strategic Alliances

APPENDIX: Supplemental Documents

REFERENCES

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